Foxp2

An interesting article published in Nature about FoxP2 (Forkhead box protein 2) gene, which has been shown to be critical for learning speech. Discovered first in a British family with inherited speech problems, foxp2 has been shown to have two amino acid differences in the human form when compared to chimpanzees. The human version, when inserted into mice, makes the mice vocalize differently (but not speak, obviously). Interestingly, neanderthals had the human form of the gene, another piece of evidence in support of the idea that neanderthals could speak.

But the function of foxp2 in the brain seems to be much broader than simply speech. In the Nature article, the researchers show that mice with the human version of foxp2 are also smarter and able to solve mazes faster than mice with their own version of foxp2. It seems that foxp2 may be important for neural plasticity.

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Nocebo effect

The Guardian has this article about the winner of the Wellcome science writing prize, which is about the Nocebo effect. This is a sort of reverse brain hacking, or brain hacking to make yourself worse off. If placebo are harmless substances that actually heal because you believe they will make you better, nocebos are harmless substances/situations/etc that cause actual harm to your health because you believe they will harm you. It’s worthwhile reading. Take a look.

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How to spot a liar/how to lie, part I

There is a lot of fascinating research on how to spot a liar–and such research has amped up in the last ten years with the increase in security consciousness. I’ve done a fair amount of reading of the literature and will discuss various aspects of the research over a few posts. I’ll start with the overview: what do all researchers agree upon?

Contrary to popular belief, there is no single, simple way to detect a liar. Shifty eyes, guilty look, halting speech–these may or may not reveal a liar. What all liars have in common, though, is that lying causes an increase in mental processing and cognitive dissonance as the liar tries to keep two contradictory idea in mind at the same time. This increase in mental processing and the disquieting nature of the cognitive dissonance are what the lie-spotter is really detecting.

This takes training, for most people. People in general are pretty bad at spotting lies, even if they think they are good at it. Judges and police officers don’t fair much better than average, although there are a few really good lie spotters. There is a technique to detecting lies, and I will get into that in future posts.

Of course, any increase in understanding about how lies are detected allow people to adjust their behavior to lie better. But no one can lie perfectly because there will always be increased difficulty involved in concealing something.

So here is one simple bit of advice: cross your fingers. What does this do? Lying, especially for people who consider themselves honest or feel bad about lying, makes people feel a little bad. In people unused to lying or concealing, this tends to show up (in stereotypical ways I will get into later). Crossing fingers behind your back brings relieves some of that guilt. The idea is that crossing your fingers is a “socially accepted” way of lying (more for kids than adults, granted). There is the feeling that the deceived would understand that it wasn’t really lying at all because the fingers were crossed. Although this is not terribly logical, it make it easier and less troubling to lie, and so less apparent.

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Stories versus models

I’ve been thinking a lot about this old Paul Krugman post, in which he discusses how hard it is for many, even serious economists, to grapple rationally with the current world financial situation. He ascribes it as a need to see economics as a morality play that punishes wrongdoers. Others have pointed out that Krugman has been right on so many major issues, despite intense resistance not only from the political class but also other economists. And the funny thing is that his correct reading of the situation doesn’t make people stop and reevaluate their assumptions.

All of this leads me to think about the difference between stories and models. The human brain is made to understand the world in terms of stories. If we see two completed unrelated things together, the brain makes up a story to connect them. That’s exactly the source of the post hoc ergo prompter hoc fallacy. That’s why jury selection works. We can’t be entirely rational in most of our understanding of the world because it is too complex. So we have certain stories about how the world works, how people should and do interact, why things happen as they do. Stories are effectively simple models that should contain the most important elements of what is going on, models that operate correctly much of the time.

Real models are carefully crafted to contain all the important elements, so that they explain the world correctly most of the time. Models are too complex to hold in our heads. They are created and run, like a computer algorithms, and sometimes they predict things that our stories never would have. Models are agnostic–if they do mix in morality or emotion they do so in defined ways. And the construction of models is scientific–if the model doesn’t work, you refine it and run it again to see if you can make it cleave better to real world behaviors.

It seems to me that economics has become much more driven by stories than models. But perhaps this is always the way things have been. It used to be that people thought that there was a natural and correct price for everything. If bread was $3 a loaf, it was unnatural and immoral to charge more. Then the model of supply and demand was created, and because the model is simple enough to be a story, people now understand that if the wheat crop fails and people are vying for fewer loaves of bread, the price will go up. But for more complex phenomenon, people are willing to come up with wilder stories when their current stories don’t model the world or create emotionally unsatisfying explanations (or not even that much more complex–witness the need of even business journalist to seek explanation for increasing fuel prices in terms of inputs like refinery shutdowns or oil shortages instead of the natural and proper corporate desire to maximize profits). People don’t trust a scientific approach to economics because they think their story explains the world, data be damned.

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Revolution images

Wow, great photo by Mauricio Lima in the New York times. Great composition. It reminds me of David’s “Liberty” painting from the French revolution. Although unfortunately there is no bare-breasted Marianne.

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The Power of Abstraction

I got into a discussion with someone recently about whether spending tens of thousands (sometimes hundreds of thousands) for a college education was really worth it. He felt that it was not, and that it was a “moral hazard” to encourage people with easy loans to get themselves well into debt.

This discussion led me to think over exactly how a college education is beneficial. I think there are many ways that it can be worth the time and money. The benefit that most people cite when talking about college is learning “critical thinking,” but I think this is really overblown. Many students take that to mean being able to criticize, and they often come out of college able to critique things, but that skill often doesn’t go over well in the job world (“I can tell you ten reasons why your idea won’t work”).

I realized that the biggest benefit of a college education is learning how to abstract things—how to model the complexities of the real world in a simplified system that can be analyzed, tweaked and applied. How to recognize when a difficult problem is really the same as a simple problem that has been solved in another field. How to cut through the clutter of seemingly unique qualities and identify the essential, universal elements.  Learning to create and apply abstraction is the most powerful think students can take from college.

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Overcoming math (and other) anxiety

Researchers recently looked at brain activity in those who have math anxiety and those who don’t. What they found was that among those who have math anxiety, through focus and concentration they could perform just as well on test as those who don’t. People who showed activation in the frontal areas of the brain performed fine. It’s also important to do that sort of focus before actually being confronted with the questions

From the study:

“Essentially, overcoming math anxiety appears to be less about what you know and more about convincing yourself to just buckle down and get to it,” Beilock said. “But if you wait till the math exam has already started to deal with your anxiety, it’s already too late,” Lyons added.

In a way, not too surprising, but perhaps useful.

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More evidence exercise rewires the brain

In this item from NYTimes Well blog, they discuss research showing that vigorous exercise can diminish the symptoms of Parkinson’s disease in ways that drugs can’t. Yet more evidence that exercise is powerful medicine for many systems in the body, including the nervous system.

One of the interesting aspects of this research is that “force” exercise (when people are compelled to keep up with a pretty rapid cadence on a tandem bike) is much more beneficial than what they call “voluntary” exercise. More evidence that intense workouts are better than mild workouts.

 

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Sleep, “energy” and mood

A new study using twitter to evaluate mood over the course of the day reveals that people’s mood rises in the morning, lowers in the afternoon, then rises again in the evening. Hmmm. Where have I seen that curve before?

This is exactly the sleepiness/wakefulness curve we highlighted in The Promise of Sleep. Yet more evidence that the amount of “energy” you have, your amount of wakefulness, is directly tied to your mood. And the reason why coffee’s greatest effect may be in its mood improvement, rather than wakefulness. Here is another recent study along these lines, showing that women who drink coffee are less depressed than those who don’t.

By the way, I don’t think that scientists really understand completely how caffeine works. The current theory is that blocks adenosine receptors in the brain. Adenosine is left over after ATP is used as a cellular energy source, so a rise in adenosine would signal that the body needs to replenish and trigger fatigue. Blocking that signal is thought to block the fatigue. I don’t really buy that is all that is happening. My guess is that there are some direct neural effects.

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Ubiquitous video and the passing of the kick-ass era

Looking at the videos of the Occupy Wall Street protest and in particular of the “pepper spray incident” I’m actually pretty hopeful. I think that it is now becoming clear to police departments and officers that there is very little they can do during protests that will not be recorded. What’s really striking in the scenes of this particular protest is that nearly every person has some sort of video-recording device and is using it. Of course police seemed to be making an effort to arrest those actively recording, but this protest should teach them that such efforts are futile.

What’s interesting is that most of the police officers are pretty calmly going about their jobs, in contrast to film of past protests I’ve seen, going back to the Vietnam era, in which it seemed like the majority of the police were really getting off on the chance to kick some ass. In this case, the pepper spraying was done by an older deputy inspector who probably hasn’t had that thrill in a while. But I’m sure he will be retiring soon. The London officer who attacked Ian Tomlinson (a newspaper vendor who took a wrong turn home, got caught up in the G20 protests and died as a result of his injuries) was finally charged with manslaughter. Not all the rogue cops are young. This guy picked out a cyclist and slammed him to the ground for fun, but his father and uncle and grandfather were also officers and he probably grew up on stories of kicking protester ass. He is no longer carrying on the family legacy. The police in Fullerton who kicked a mentally ill man to death are being charged with murder, which would not have happened without video.

I think we are seeing the passing of an era. Everyone is realizing you just can’t do this stuff and get away with it. There will still be cases of excessive force, and police will try to confiscate all cameras, but it is ultimately a futile effort. And the officers for whom kicking ass is one of the attractions of the job (my guess is that some are actually addicted to it) will, eventually, be weeded out. And newer officers won’t understand what the attraction was in the first place.

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